Projects
ADAPT SMART
Accelerating early access to innovative medicines for appropriate patient groups
The IMI ADAPT SMART project launched in September 2015. It is an enabling platform that supports activities related to Medicines Adaptive Pathways to Patients (MAPPs) within the Innovative Medicines Initiative (IMI). MAPPs seek to foster access to beneficial treatments for appropriate patient groups at the earliest appropriate stage in the lifecycle.
€3.1 M
funding from IMI2 and EFPIA
32
international partners
About ADAPT SMART
The ADAPT SMART* platform allows for all stakeholders to coordinate MAPP-related activities and to distribute key findings. It also aims to identify the scientific challenges and opportunities that might arise during the adoption of MAPPs. Outcomes from the consortium will inform future research agendas and provide a basis for discussing approaches to the implementation of MAPPs. Visit the ADAPT SMART website for more information.
*Accelerated Development of Appropriate Patient Therapies: a Sustainable, Multi-stakeholder Approach from Research to Treatment-outcomes.
Coordinating multi-stakeholder dialogue
The project reaches out to all stakeholders involved in the pathway of a medicine, from development to patient. Its international consortium brings together 32 partners, including the European Medicines Agency which fulfills the project leader role. Lygature coordinates the consortium, with roles and responsibilities that include:
- Program management. Lygature is responsible for overall program management, with the goal of supporting and monitoring effective execution of the work plan, including control of deliverables, milestones, and budgets.
- Coordination and leadership. Lygature is a co-lead in Work Package 2 of the project. This Work Package develops a roadmap for the MAPPs process for products, involving all phases of development and licensing as well as all relevant stakeholders (e.g. HTA, payers, clinical practice).
- Trusted partner. As an independent partner, Lygature safeguards different public and private interests from the proposal phase to the results phase, ensuring strict confidentiality.
ADAPT SMART is the first project under IMI to bring together, within a strategic policy, project stakeholders that include industry, regulatory authorities, patient organizations, physicians, health technology assessment institutions, and payers. It is a prime example of the Lygature mission to coordinate and combine complementary areas of expertise, and potentially different interests, in order to accelerate access to beneficial treatment options for appropriate patient groups.
Lygature together with
Abbvie, Amgen, Astellas, AstraZeneca, Bayer HealthCare, Boehringer-ingelheim, Bristol-Myers Squibb, Casmi, European Federation of Pharmaceutical Industries and Associations, European Medicines Agency, European Patients Forum, EURORDIS, GlaxoSmithKline, Haute Autorité de Santé, Ipsen, Janssen, Lilly, H. Lundbeck A/S, Lysogene, Merck KGaA, MIT NEWDIGS, MSD, NICE, Novartis, Novo Nordisk, Pfizer, Roche, Sanofi, Sundheds Styrelsen, UCB, Zorginstituut Nederland
Acknowledgement of support
This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 115890. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA.
Project updates
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ADAPT SMART contributes at the “Innovation for Patients” conference
On 1 and 2 March 2016, the Dutch Ministry of Health organized the “Innovation for Patients” conference in Amsterdam, on the topic of bringing medicines to patients faster at acceptable costs. Minister Edith Schippers (Health, Welfare and Sport) invited a broad range of experts, including members from the IMI ADAPT SMART project, to discuss challenges and opportunities faced. For more information about the conference and the topics discussed, please refer to the press release issued by the ministry (in Dutch).
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André Broekmans, coordinator ADAPT SMART, looks ahead
With the first few months of the ADAPT SMART project underway, coordinator André Broekmans shares his views on what is needed to continue to drive the project forward. In addition, Broekmans and Luk Maes (Work Package 2 Leads) also met in December to discuss the ambitious objectives of ADAPT SMART, the impact of the diverse participants involved in the project, and what sets this initiative apart from other programs focussed on MAPPs, which resulted in a Podcast.
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ADAPT SMART Launch in the News
ADAPT SMART launched on Friday September 4th, 2015. Click here for a collection of headlines inspired by the event.