Projects
PD-MIND
A clinical trial to find a potential cure for Parkinson’s Disease. (The trial is continued with other funding.)
Currently there is an unmet clinical need to treat Parkinson disease with mild cognitive impairment (PD-MCI). In fact, nicotinic agonists are specifically relevant for this condition. Hence, the major aim of the project PD-MIND is to identify the potential of the nicotinic α7 agonist AZD0328 in a randomized, placebo-controlled, parallel group, international multicentre study on cognitive function in people diagnosed with PD-MCI.
€ 2.1 M
funding from IMI and EFPIA
9
European Partners
About PD-MIND
PD-MIND’s ambition is to determine the potential effectiveness of a nicotinic receptor agonist on cognitive decline as a primary outcome measure in PD-MCI.
This could be the first systematic evidence of improvement in PD-MCI, an important and widespread condition, inasmuch as the project aims to develop a drug for the first phase 3 clinical trial for PD-MCI. Since PD affects 1% of European citizens over 65 years, this envisioned outcome is expected to have a huge socioeconomic and clinical impact.
Lygature in PD-MIND
Providing multi-disciplinary partnership management, as well as communication and dissemination expertise.
- Program management. Lygature is responsible for the overall management of the PD-MIND project such as ensuring scientific dialogue and communication across the consortium, efficient administration and timely reporting. Moreover, Lygature is responsible for information distribution within the consortium and facilitation of internal communication, a.o. by providing their proprietary “MyProjectPlaza” communication platform. This ensures transparency, efficient clarification and fine-tuning among partners. Lastly, Lygature provides impartial legal advice in various negations during the project.
- Communication and Dissemination. Lygature supports the engagement of important to the project stakeholders by establishing the communication channels through which PD-MIND will effectively interact with its key-stakeholders and support patient recruitment. Lygature will develop the project website and the communications, dissemination and exploitation plan which will contain key instruments for an effective dissemination policy.
Lygature together with
Acknowledgement of support
PD-MIND receives funding from the Innovative Medicines Initiative 2 Joint Undertaking under grant agreement No 820880. This Joint Undertaking receives support from the European Union’s Horizon 2020 research and innovation programme and EFPIA. See www.imi.europa.eu for more details.
Project updates
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The Michael J Fox Foundation supports the PD-MIND project
A new collaborative project launched in May 2019: PD-MIND’s ambition is to determine the potential effectiveness of a nicotinic receptor agonist on cognitive decline as a primary outcome measure in PD-MCI.
The Michael J Fox Foundation for Parkinson’s Research supports the PD-MIND project by providing €182.000 for an extended MRI imaging program. This funding supports the development of useful biomarkers relevant to the PD-MIND project.