Projects
Translational Research IT (TraIT)
Implementing and sustaining a long-lasting IT infrastructure for translational research
Translational research programs depend increasingly on a diverse collection of complex datasets that are often phenomenal in size. To ensure maximum benefit, integrated tools for data collection, analysis and management are required, as well as an infrastructure that supports collaboration between research centers. The Translational Research IT (TraIT) project was launched in October 2011 to address these informatics challenges.
€19 M
funding from FES, VWS & partners
>4,000
users as of March 2017
About TraIT
The Translational Research IT (TraIT) project provides an easy-to-access and easy-to-use infrastructure for data sharing, together with a set of tools for further exploration of the collected data. It operates across the four major domains of translational research: clinical, imaging, biobanking, and experimental (any-omics). TraIT gives scientists within multi-site projects the resources needed to share and disseminate data and analyses. Importantly, the project aimed to adopt and adapt existing and proven solutions (e.g. XNAT, Ldot, cBioPortal) rather than embarking on major software development projects. As of January 2020, more than 4000 researchers from over 400 studies and dispersed over more than 500 locations are making use of one or more of TraIT’s services. Visit the TraIT website for more information about the project.
Realizing sustainable infrastructure for biomedical research
Since its inception, TraIT has grown from 11 to 32 participating organizations, including all Dutch university medical centers, charities, and a variety of private partners. CTMM initiated the project in close collaboration with members of the research community, identifying opportunities for partnerships and developing an efficient and well-defined management structure. From January 2016, CTMM’s roles and responsibilities within TraIT are provided under the Lygature brand, while the core TraIT facilities are integrated into Health-RI as of January 2020:
- Governance. Lygature is the legal entity coordinating TraIT. It takes responsibility for sustainability and legal discussions around the setup of a long lasting infrastructure for the Dutch and international biomedical community. In addition, Lygature provides financial management.
- Innovation activities. To ensure sustainability, Lygature collaborates with consortium partners to attract new funding for maintenance and extension of the TraIT infrastructure in the context of Health-RI. Lygature is pivotal in creating strategic alliances with other infrastructure organizations (national and international), research funders, and patient representatives, so that further development can take place.
- Operations. Lygature heads the operations team, which works on professional deployment of infrastructure, and of quality and service management. The team also handles end-user support and education, as well as branding and communications.
TraIT is an important example of Lygature’s mission to bring academia, industry, and society together in research infrastructure projects that allow participants to benefit from shared resources and data. It has required extensive expertise in data infrastructure, management, and science, and has helped to build many long-term partnerships. Lygature, together with the TraIT partners, continues to foster these partnerships.
Lygature together with
Academic Medical Center, Computer Sciences Corp, CTMM, Dutch Cancer Foundation, Dutch Heart Foundation, Dutch Techcentre for Life Sciences, Erasmus Medical Center, Erasmus University Rotterdam, Genalice, GlaxoSmithKline, The Hyve, ICIN Netherlands Heart Institute, Keosys, Leiden University Medical Center, Maastro Clinic, Maastricht University Medical Center, Netherland Bioinformatics Centre (participation ended), Netherlands Cancer Institute, Netherlands eScience Center, OpenClinica, OpenText, Parelsnoer Institute, Radboud University Medical Center, Royal Philips, Roche Diagnostics, SURFsara, University Medical Center Groningen, University Medical Center Utrecht, Vancis, VU University Amsterdam, VU University Medical Center
Project updates
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TraIT celebrates its 2000st user
Lucy Pike (2000st user, right) and Nikie Hoetjes (left) during a PETRA consortium meeting in Guy’s and St. Thomas’ in London.
2015 has seen more than a doubling of researchers that enroll to use one of the tools and services provided by CTMM-TraIT. At the end of November, Nikie Hoetjes, research analyst for the PETRA consortium at the VUmc, requested access to NBIA for Lucy Pike, a clinical scientist of the PET center of the Guy’s and St. Thomas Hospital in London. Read more
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HOVON Pathology Facility and Biobank web portal via TraIT
The HOVON Pathology Lymphoma Working Group launched their new sample request/tracking portal in close collaboration with the TraIT Biobanking team and CSC developers. Read more
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Meet us at the Empowering Personalized Medicine and Health Research conference in Amersfoort
Personalized medicines is recognized as the next big dot on the horizon for health care. The conference offers an insight into current and future developments, as well as initiatives to connect biomedical scientist, informaticians, clinicians, patientcare and industry. The TraIT team will be present at the conference. Visit www.nlhealthresearch.nl for more information.